RTN4IP1 Antibody, HRP conjugated

Code CSB-PA848832LB01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) RTN4IP1 Polyclonal antibody
Uniprot No.
Target Names
RTN4IP1
Alternative Names
MGC12934 antibody; mitochondrial antibody; NIMP antibody; NOGO interacting mitochondrial protein antibody; NOGO-interacting mitochondrial protein antibody; Reticulon 4 interacting protein 1 antibody; Reticulon 4 interacting protein 1, mitochondrial antibody; Reticulon-4-interacting protein 1 antibody; RT4I1_HUMAN antibody; Rtn4ip1 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Reticulon-4-interacting protein 1, mitochondrial protein (41-396AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
HRP
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Plays a role in the regulation of retinal ganglion cell (RGC) neurite outgrowth, and hence in the development of the inner retina and optic nerve. Appears to be a potent inhibitor of regeneration following spinal cord injury.
Gene References into Functions
  1. Recessive Mutations in RTN4IP1 Cause Isolated and Syndromic Optic Neuropathies. PMID: 26593267
  2. RTN4IP1 has a tumor-suppressive function and may regulate thyroid cancer progression. PMID: 23393170
Involvement in disease
Optic atrophy 10 with or without ataxia, mental retardation, and seizures (OPA10)
Subcellular Location
Mitochondrion outer membrane.
Protein Families
Zinc-containing alcohol dehydrogenase family, Quinone oxidoreductase subfamily
Tissue Specificity
Widely expressed in mitochondria-enriched tissues. Found in heart, muscle, kidney, liver, brain and placenta.
Database Links

HGNC: 18647

OMIM: 610502

KEGG: hsa:84816

STRING: 9606.ENSP00000358059

UniGene: Hs.155839

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